First Case of 2019 Novel Coronavirus in the United States

N Engl J Med. 2020 Mar 5;382(10):929-936. doi: 10.1056/NEJMoa2001191. Epub 2020 Jan 31.

First Case of 2019 Novel Coronavirus in the United States.

Holshue ML1, DeBolt C1, Lindquist S1, Lofy KH1, Wiesman J1, Bruce H1, Spitters C1, Ericson K1, Wilkerson S1, Tural A1, Diaz G1, Cohn A1, Fox L1, Patel A1, Gerber SI1, Kim L1, Tong S1, Lu X1, Lindstrom S1, Pallansch MA1, Weldon WC1, Biggs HM1, Uyeki TM1, Pillai SK1; Washington State 2019-nCoV Case Investigation Team.

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Abstract

An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.Copyright © 2020 Massachusetts Medical Society.


PMID: 32004427 DOI: 10.1056/NEJMoa2001191